Low TSH Levels Are a Risk Factor for Alzheimer's Disease
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Low TSH Levels Are a Risk Factor for Alzheimer's Disease

by Mary Shomon

June 2004 -- A study published in the June 8th issue of the journal Neurology indicates that low thyroid-stimulating hormone (TSH) levels may be linked to a risk of developing Alzheimer's disease. British researchers measured TSH levels in 178 patients with Alzheimer's disease, and 291 control subjects with normal TSH levels. The patients with Alzeimers had lower TSH compared to the control subjects, resulting in a two-fold increased risk of Alzheimer's disease in peope with lower TSH levels.

The article states: "Low TSH levels could be a consequence of Alzheimer-related neuro-degeneration leading to reduced hypothalamic thyrotropin-releasing hormone (TRH) secretion or decreased pituitary responsiveness and consequently low TSH levels. Low TSH or TRH levels could also precede dementia."

Source: Neurology 2004;62:1967-1971.



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