Mild Hypothyroidism and its Effect on Cognitive Status
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Mild Hypothyroidism and its Effect on Cognitive Status

by Mary Shomon

June 2004 -- While more severe clinical hypothyroidism is associated with various neuropsychological and cognitive changes -- and is one of the causes of reversible dementia -- whether or not similar symptoms are seen in people with mild hypothyroidism is controversial. Italian researchers set out to assess the cognitive and psychological function in a group of people who were recently diagnosed as mildly hypothyroid, and who had minor symptoms.

After treatment with levothyroxine, the patients studied generally had improved verbal fluence, less depression, and improved mood, leading the researchers to conclude that treatment of asymptomatic mild hypothyroidism is recommended, both to re-set hormonal levels and, particularly in older subjects, to protect the brain against the potential risk of cognitive and psychological dysfunction.

Source: Bono G, et. al., "Cognitive and affective status in mild hypothyroidism and interactions with l-thyroxine treatment." Acta Neurol Scand. 2004 Jul;110(1):59-66.



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