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Table of Contents Book Introduction Reviews Autoimmune Risks/Symptoms Checklist |
Author: Mary J. Shomon
ISBN number: 0060938196
List price: $14.95 (US dollars)
Published by: HarperCollins, HarperResource
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Collaboration Advances Potential Therapy for Autoimmune Diseases (June 2002)
In June of 2002, the Department of Energy's Pacific Northwest National Laboratory announced the launch of a collaboration with two U.S. companies and Russian scientists to develop a more effective treatment for autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. The collaboration represents the latest commercial venture between a former Russian weapons facility, a DOE national laboratory and U.S. industry under DOE's Initiatives for Proliferation Prevention program (IPP).
Through a Cooperative Research and Development Agreement, Advanced Biotherapy Inc. of Woodland Hills, Calif., and New Horizon Diagnostics Inc. of Columbia, Md., will hold nonexclusive licenses to inventions created by scientists at the Institute of Immunological Engineering of Moscow or by PNNL researchers through this program.
The Russian scientists have created unique humanized antibodies to gamma interferon, a protein that when overproduced triggers and worsens various autoimmune conditions. This work is a major step toward creating a much-improved treatment for certain autoimmune diseases. Until recently, most treatments employed antibodies (proteins that bind to and disable foreign proteins, called antigens) derived from mice, which were effective but could be used only one or two times before the human body rejected them. But with human antibodies, the human body potentially could accept them over longer periods of time, thus providing for long-term treatment.
DOE's IPP http://www.nn.doe.gov/ipp.shtml program funded this research with the goal of creating non-defense jobs for former Soviet weapons scientists by linking them with U.S. companies interested in commercializing their non-weapons technologies. IPP projects have engaged more than 500 former weapons scientists in pursuing commercial applications.
SOURCE: University At Buffalo (http://www.buffalo.edu/), Release date: June 3, 2002
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